Meru Chem Private Limited

For Remineralization & Dentin Hypersensitivity Relief Toothpaste Formulas

Nano-hydroxyapatite (nano-HA) has gained prominence in oral care due to its unique properties. Let us explore its role in toothpaste formulations :

• Composition and Structure : Nano-HA is a synthetic form of hydroxyapatite (HA), a mineral naturally found in teeth and bones that have chemical formula is Ca₁₀(PO₄)₆(OH)₂.

Our Nano-HA particles are incredibly small, between 30-50 nm crystallite size by XRD measurements & thus enhancing their efficacy when used in oral hygiene formulas like toothpastes & dental tablets.

• Remineralization : Studies have shown that nano-HA can remineralize initial caries lesions. Nano-HA acts as a calcium & phosphate reservoir, maintaining a state of supersaturation at the tooth surfaces and allows replenishment of depleted calcium and phosphorus ions. This promotes crystal deposition and growth, strengthening the enamel.
• Dentin Hypersensitivity Relief : Dentin hypersensitivity (DHS) causes sharp pain due to exposed dentin tubules. Nano-HA-containing toothpastes have been effective in reducing DHS symptoms. They physically occlude dentin tubules, providing relief.
• Clinical Evidence : Clinical trials have demonstrated that toothpaste with 15% nano-HA significantly reduces DHS. Nano-HA alone or supplemented with potassium nitrate performs as well as commercial desensitizing dentifrices. Nano-hydroxyapatite toothpaste offers a promising avenue for improving oral health. Its remineralization properties and DHS relief make it a valuable addition to modern dental care.

Beyond remineralization and dentin hypersensitivity relief, nano-hydroxyapatite (nano-HA) containing toothpastes offers additional benefits:

• Enamel Strengthening : Nano-HA reinforces tooth enamel by promoting crystal growth and enhancing its structural integrity. It helps prevent enamel demineralization caused by acidic foods and beverages.
• Anti-Plaque Properties : Nano-HA particles have a high surface area, allowing them to interact with plaque biofilms. They inhibit bacterial adhesion and reduce plaque formation, contributing to better oral hygiene.
• Whitening Effect : Nano-HA gently polishes tooth surfaces, removing surface stains. Over time, this can lead to a gradual improvement in tooth color.
• Long-Term Protection : Regular use of nano-HA toothpastes provides ongoing protection against enamel erosion and sensitivity. It is an initiative-taking approach to maintaining oral health.